PEMF( Pulsed Electromagnetic Field therapy) Health Benefits

PEMF( Pulsed Electromagnetic Field therapy) Health Benefits

PubMed Studies - Some peer-reviewed research studies on the health benefits of pulsed electromagnetic field therapy.


The effect of EMF on the immune system in phagocytic cells alone has attracted attention because of the role that extremely low-frequency electromagnetic field (ELF-EMF) plays in decreasing the growth rate of bacteria. 

Immunological studies show that low-intensity EMF can interact with cells and tissues, providing a large number of anti-inflammatory and wound healing applications.

An introduction to electromagnetic field therapy and immune function: a brief history and current status (J Sci Appl: Biomed. 2015 Vol 3, Issue 2)

PEMF treatment leads to gene expression changes of the factors involved in regulating inflammation, including inflammation resolution.

Effect of pulsed electromagnetic field treatment on programmed resolution of inflammation pathway markers in human cells in culture (J Inflamm Res. 2015; 8: 59–69)


The effect of low-frequency electromagnetic field on human bone marrow stem/progenitor cell differentiation (Stem Cell Research, Volume 15, Issue 1, July 2015, Pages 96–108)

Complex interactions of multiple genetic substances give rise to physical cues, including mechanical and electrical signals that are relatively easier to control and implement in order to guide repair and regeneration. Treatment using EMF could be an auxiliary approach to enhancing cellular activities for tissue regeneration by stimulating cells with both EMF and the proper chemical signals (differentiation media and growth factors) to promote cellular responses synergistically. Additionally, this inherently noninvasive and noncontact treatment method is easily applied to cells for tissue regeneration using three-dimensional scaffolds

Effects of pulsed electromagnetic field frequencies on the osteogenic differentiation of human mesenchymal stem cells (Orthopedics. 2012 Apr;35(4):e526-31)

The results of the current study show that pulsed electromagnetic field frequency is an important factor with regard to the induction of human mesenchymal stem cell differentiation. Furthermore, a pulsed electromagnetic field frequency of 50 Hz was the most effective at inducing human mesenchymal stem cell osteoblast differentiation in vitro.


Pulsed electromagnetic field improves cardiac function in response to myocardial infarction (Am J Transl Res. 2014; 6(3): 281–290)

PEMF treatment significantly inhibited cardiac apoptosis and improved cardiac systolic function. Moreover, PEMF treatment increased capillary density, the levels of vascular endothelial growth factor (VEGF) and hypoxic inducible factor-1α in infarct border zone. Furthermore, the number and function of circulating endothelial progenitor cells were advanced in PEMF treating rats.

Pulsed electromagnetic field therapy promotes healing and microcirculation of chronic diabetic foot ulcers: a pilot study (Adv Skin Wound Care. 2015 May;28(5):212-9)

By the end of the treatment period, there was an 18% decrease in wound size in the active PEMF group as compared with a 10% decrease in the control group. The PEMF group demonstrated significant cumulative increase in cutaneous capillary blood velocity (by 28%) and 14% increase in capillary diameter. In contrast, the control group showed a decrease in both capillary blood velocity and diameter.


Combination of Local Transplantation of In Vitro Bone-marrow Stromal Cells and Pulsed Electromagnetic Fields Accelerate Functional Recovery of Transected Sciatic Nerve Regeneration: A Novel Approach in Transected Nerve Repair (Curr Neurovasc Res. 2015;12(3):222-31)

The regenerated nerve fibers were studied within 12 weeks after surgery. Behavioral, functional, electrophysiological, biomechanical, gastrocnemius muscle mass findings, morphometric indices and immuonohistochemical reactions confirmed faster recovery of regenerated axons in BMSC/PEMF group compared to those in the other groups (P<0.05). The use of undifferentiated BMSCs with whole body exposure to PEMF improved functional recovery. Combination of local transplantation of in vitro bone-marrow stromal cells and pulsed electromagnetic fields could be considered as an effective, safe and tolerable treatment for peripheral nerve repair in clinical practice.


Desynchronization of Human Circadian Rhythms (Jpn J Physiol. 1967;17:450-457)

Fifty human subjects have been kept in an underground bunker in conditions of continuous illumination, each in complete isolation and without any time-telling device… 9 subjects showed different circadian frequencies in activity and in body temperature; in two of these subjects, desynchronization started immediately after being enclosed in the bunker, in the remaining 7 subjects after 9 to 23 days of confinement.

The effects of electric fields on circadian rhythmicity in men (Life Sci Space Res. 1970;8:177-87)

In an underground bunker built for the study of human circadian rhythms, one of the two experimental rooms is shielded against natural magnetic and electric fields… real internal desynchronization has been observed only in the shielded room… the total of the natural electromagnetic fields shortens the circadian period, and it strengthens the interaction between activity rhythm and the vegetative rhythms. Artificial constant fields, electric and magnetic, do not influence human circadian rhythms. However, a weak electric field, alternating with a frequency of 10 Hz, affects human circadian rhythms in the same manner as the total of the natural fields… with circadian rhythms as an indicator, natural electromagnetic fields are proved to be effective on human beings for the first time; this may be of interest with regard to space where these fields are absent.